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KCNQ2 Cure Alliance Research Roundtable 2026
Saturday, September 19
 

7:30am CEST

Breakfast and Registration
Saturday September 19, 2026 7:30am - 8:00am CEST
Centro Congressi Federico II
Saturday September 19, 2026 7:30am - 8:00am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Breakfast, Subtype1, Subtype2

8:00am CEST

Welcome and Overview
Saturday September 19, 2026 8:00am - 8:15am CEST
Centro Congressi Federico II

Speakers
avatar for Brooke Babineau, PhD

Brooke Babineau, PhD

KCNQ2 Cure Alliance
Brooke is currently a Senior Scientist at Encoded Therapeutics, where she leads drug development initiatives to provide therapeutic options for pediatric central nervous system disorders, including developmental epileptic encephalopathies. Brooke has a lifelong passion for serving... Read More →
Saturday September 19, 2026 8:00am - 8:15am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 1: Mislocalization

8:15am CEST

Mapping KCNQ2 DEE: Disease Mechanisms, Channel Mislocalization, and Cortical Proteomic Signatures
Saturday September 19, 2026 8:15am - 8:30am CEST
Centro Congressi Federico II

Speakers
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 8:15am - 8:30am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 1: Mislocalization

8:30am CEST

Postsynaptic KCNQ Channels at Excitatory Synapses and Their Impact on Developmental and Epileptic Encephalopathy
Saturday September 19, 2026 8:30am - 8:45am CEST
Centro Congressi Federico II

Speakers
HJ

Hee Jung Chung, PhD

University of Illinois at Urbana-Champaign

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 8:30am - 8:45am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 1: Mislocalization

8:45am CEST

Panel Discussion and Q&A
Saturday September 19, 2026 8:45am - 9:00am CEST
Centro Congressi Federico II

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 8:45am - 9:00am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 1: Mislocalization

9:00am CEST

Gene Therapy for KCNQ2 DEE
Saturday September 19, 2026 9:00am - 9:15am CEST
Centro Congressi Federico II

Speakers
YC

Yong Cheng, PhD

Minzu University of China

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 9:00am - 9:15am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 2: Therapeutics I

9:15am CEST

Development and Evaluation of Systemic AAV Gene Therapy to Treat Neonatal KCNQ2 Epileptic Encephalopathy
Saturday September 19, 2026 9:15am - 9:30am CEST
Centro Congressi Federico II

Speakers
RE

Rana Eser, PhD

California Institute of Technology

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 9:15am - 9:30am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 2: Therapeutics I

9:30am CEST

Targeted Approach for KCNQ2-DEE With a Novel Engineered AAV Gene Therapy
Saturday September 19, 2026 9:30am - 9:45am CEST
Centro Congressi Federico II

Speakers
NG

Nick Goeden, PhD

Asymptote Genetic Medicine

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 9:30am - 9:45am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 2: Therapeutics I

9:45am CEST

Panel Discussion and Q&A
Saturday September 19, 2026 9:45am - 10:00am CEST
Centro Congressi Federico II

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 9:45am - 10:00am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 2: Therapeutics I

10:00am CEST

Break
Saturday September 19, 2026 10:00am - 10:15am CEST
Centro Congressi Federico II
Saturday September 19, 2026 10:00am - 10:15am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Break

10:15am CEST

QRL-101: A Kv7.2/7.3 Modulator for the Treatment of Rare Epilepsy
Saturday September 19, 2026 10:15am - 10:30am CEST
Centro Congressi Federico II

Speakers
MM

Manoj Malhotra

Chief Medical Officer, QurAlis
Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 10:15am - 10:30am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 3: Therapeutics II

10:30am CEST

Toward Scalable Precision Therapeutics for KCNQ2-DEE
Saturday September 19, 2026 10:30am - 10:45am CEST
Centro Congressi Federico II

Speakers
AS

Aubrie Soucy Verran, MLA

Boston Children’s Hospital

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 10:30am - 10:45am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 3: Therapeutics II

10:45am CEST

Antisense Oligonucleotide Treatment: Application of the N-of-1 Paradigm
Saturday September 19, 2026 10:45am - 11:00am CEST
Centro Congressi Federico II

Speakers
TS

Tristan Sands, MD, PhD

Columbia University

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 10:45am - 11:00am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 3: Therapeutics II

11:00am CEST

Extended Discussion: Delivering Treatments to Patients (Breakout Groups: Small Molecule, ASO, Gene Therapy)
Saturday September 19, 2026 11:00am - 11:45am CEST
Centro Congressi Federico II

Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 11:00am - 11:45am CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 3: Therapeutics II

11:45am CEST

Lunch and Posters
Saturday September 19, 2026 11:45am - 1:15pm CEST
Centro Congressi Federico II
Saturday September 19, 2026 11:45am - 1:15pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Lunch

1:15pm CEST

Patient Registries vs. Natural History Studies: What’s the Difference?
Saturday September 19, 2026 1:15pm - 1:45pm CEST
Centro Congressi Federico II

Speakers
IS
Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 1:15pm - 1:45pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 4: Natural History and Registries

1:45pm CEST

European KCNQ2 Research: Biomarkers, Natural History, and Therapeutic Development
Saturday September 19, 2026 1:45pm - 2:15pm CEST
Centro Congressi Federico II

Speakers
SW

Sarah Weckhuysen, MD, PhD

University of Antwerp

Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 1:45pm - 2:15pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 4: Natural History and Registries

2:15pm CEST

Natural History and Registries: A Call to Action
Saturday September 19, 2026 2:15pm - 2:45pm CEST
Centro Congressi Federico II

Speakers
IB

Isabella Brambilla

European KCNQ2 Association
Moderators
MT

Maurizio Taglialatela, MD, PhD

University of Naples Federico II

Saturday September 19, 2026 2:15pm - 2:45pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 4: Natural History and Registries

2:45pm CEST

Extended Discussion: KCNQ2 Coordination and Facilitating Global Collaboration on Registries and Natural History Studies
Saturday September 19, 2026 2:45pm - 3:15pm CEST
Centro Congressi Federico II

Saturday September 19, 2026 2:45pm - 3:15pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 4: Natural History and Registries

3:15pm CEST

Break
Saturday September 19, 2026 3:15pm - 3:30pm CEST
Centro Congressi Federico II
Saturday September 19, 2026 3:15pm - 3:30pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Break

3:30pm CEST

Antisense Oligonucleotides for KCNQ2
Saturday September 19, 2026 3:30pm - 4:00pm CEST
Centro Congressi Federico II

Speakers
SP

Steven Petrou, PhD

Praxis Medicines

Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 3:30pm - 4:00pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 5: Special Topics

4:00pm CEST

From Channel Biophysics to Neuronal Excitability: Mechanisms of KCNQ Dysfunction in Neurodevelopmental Disorders
Saturday September 19, 2026 4:00pm - 4:15pm CEST
Centro Congressi Federico II

Speakers
RB

Rene Barro-Soria, PhD

University of Miami

Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 4:00pm - 4:15pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 5: Special Topics

4:15pm CEST

A Framework for Quantitative Motor Phenotyping in KCNQ2-Related Neurodevelopmental Disorders
Saturday September 19, 2026 4:15pm - 4:30pm CEST
Centro Congressi Federico II

Speakers
SB

Sunanjay Bajaj, MD

UTHealth Houston

Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 4:15pm - 4:30pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 5: Special Topics

4:30pm CEST

Establishing a Humanized KCNQ2 p.G281R Mouse as a Preclinical Model for Therapeutic Discovery
Saturday September 19, 2026 4:30pm - 4:45pm CEST
Centro Congressi Federico II

Speakers
AA

Anil Aturk, PhD

The Jackson Laboratory

Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 4:30pm - 4:45pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 5: Special Topics

4:45pm CEST

Panel Discussion and Q&A
Saturday September 19, 2026 4:45pm - 5:00pm CEST
Centro Congressi Federico II

Moderators
AT

Anastasios Tzingounis, PhD

Children's Hospital of Philadelphia
This is a brief bio.
Saturday September 19, 2026 4:45pm - 5:00pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
  Session 5: Special Topics

5:00pm CEST

Wrap-Up and Thanks
Saturday September 19, 2026 5:00pm - 5:15pm CEST
Centro Congressi Federico II

Speakers
avatar for Brooke Babineau, PhD

Brooke Babineau, PhD

KCNQ2 Cure Alliance
Brooke is currently a Senior Scientist at Encoded Therapeutics, where she leads drug development initiatives to provide therapeutic options for pediatric central nervous system disorders, including developmental epileptic encephalopathies. Brooke has a lifelong passion for serving... Read More →
Saturday September 19, 2026 5:00pm - 5:15pm CEST
Centro Congressi Federico II Via Partenope, 36, 80121 Napoli NA, Italy
 

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Saturday, September 19
Centro Congressi Federico II
  • Break
  • Breakfast
  • Lunch
  • Session 1: Mislocalization
  • Session 2: Therapeutics I
  • Session 3: Therapeutics II
  • Session 4: Natural History and Registries
  • Session 5: Special Topics